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VOL. 9, ISSUE 8 (2024)
Chemical profiling and toxicological assessment of bee product propolis from Assam, India: Implications for health and safety
Authors
Trinayan Barthakur, Akalesh Kumar Verma, Namram Sushindrajit Singh, Diksha Dutta
Abstract
Propolis, a natural resinous substance produced by honeybees from
diverse botanical sources, offers a myriad of therapeutic properties owing to
its varied plant origins. This study focuses on propolis collected from the
bio-diverse region of Assam, India, situated in the North-Eastern state. The
rich biodiversity of this area suggests the presence of a diverse array of
phytochemicals with potential therapeutic benefits. Our research aims to identify
and analyse the phytochemicals composition of the Assam propolis sample, while
also investigating its possible impact on haematological parameters and sperm
toxicityprimarily focussing on sub-acute toxicity study. Qualitative
phytochemical screening showed high concentration of secondary metabolites like
alkaloids, flavonoids, and phenols. Haematological studies revealed a stark
increase in RBC count, haemoglobin, %PCV and %RDW. Although the percentage
neutrophil exhibited a sharp increase, the lymphocyte population experienced a
decreasing trend with respect to control. There was also an increase in ALT and
AST suggesting that there may be a certain degree of hepatotoxicity. The study
also showed a deviation from the normal sperm morphology in a time-dependent
manner.
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Pages:154-162
How to cite this article:
Trinayan Barthakur, Akalesh Kumar Verma, Namram Sushindrajit Singh, Diksha Dutta "Chemical profiling and toxicological assessment of bee product propolis from Assam, India: Implications for health and safety". International Journal of Entomology Research, Vol 9, Issue 8, 2024, Pages 154-162
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