ARCHIVES
VOL. 11, ISSUE 1 (2026)
Phytochemical analysis and In vitro bioactivities of Syzygium cumini seed extract: Larvicidal/Pupicidal and Antidiabetic Potential
Authors
Govindaraj Naveena, Sabapathy Vijayakumar, Murugaiyan Annathurai, Palanivel Vanishree, Shanmugasundaram Somu, Veeramani Dhanalakshmi
Abstract
Syzygium cumini seeds
were subjected to qualitative phytochemical screening, revealing the presence
of alkaloids, flavonoids, tannins, phenolics, saponins, terpenoids, steroids,
glycosides, and carbohydrates, with proteins and amino acids absent. The
extract demonstrated significant larvicidal and pupicidal activity
against Aedes aegypti, with mortality rates increasing dose-dependently
across all instars and pupal stages. The lowest LC50 value
(118.202 µg/mL) was observed for the 1st instar larvae, indicating higher
susceptibility compared to later stages and pupae. Morphological assessment of
treated 3rd instar larvae via microscopy revealed visible deformities and
inhibition of normal development. Additionally, the extract exhibited
notable in vitro antidiabetic potential, likely attributed to its
rich phytochemical profile, particularly flavonoids and alkaloids, which are known
for bioactive properties. These findings suggest that Syzygium cumini seed
extract holds promise as a natural, eco-friendly agent for mosquito vector
control and as a potential source of antidiabetic compounds, warranting
further in vivo studies.
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Pages:449-453
How to cite this article:
Govindaraj Naveena, Sabapathy Vijayakumar, Murugaiyan Annathurai, Palanivel Vanishree, Shanmugasundaram Somu, Veeramani Dhanalakshmi "Phytochemical analysis and <i>In vitro </i>bioactivities of <i>Syzygium cumini</i> seed extract: Larvicidal/Pupicidal and Antidiabetic Potential". International Journal of Entomology Research, Vol 11, Issue 1, 2026, Pages 449-453
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