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VOL. 10, ISSUE 9 (2025)
Biogenic bismuth nanoparticles from Eclipta prostrata Leaves: A natural source of antioxidant, antimicrobial and cytotoxic agents
Authors
P Vijaya Kumari, G Reshma, J Hemapriya, R Elaiyaraja
Abstract
Eclipta prostrata
(L.) L., often referred to as Eclipta alba or False daisy, is a traditional
herbal remedy from the Asteraceae family, prevalent in tropical and subtropical
areas. It has been utilized for generations in Indian, Nepalese, and
Bangladeshi medicine to address skin problems, liver conditions, and digestive
issues. This research investigates the antioxidant, antimicrobial, and
cytotoxic properties of biogenically produced Bismuth Nanoparticles (Bi NPs).
The activity of scavenging free radicals was assessed using several in vitro
methods, such as DPPH, ABTS, FRAP, and radical scavenging assays, all
indicating significant free radical neutralization and reducing capacity,
highlighting the potential of biogenically synthesized bismuth nanoparticles to
mitigate oxidative stress—a key factor in various chronic illnesses. The
antibacterial and antifungal effects were assessed against bacterial and fungal
strains, revealing notable zones of inhibition that corroborate its traditional
application in infection treatment. The Brine shrimp lethality assay (Artemia
bioassay) was utilized to evaluate cytotoxicity, showing a dose-dependent rise
in mortality, indicating possible anticancer effects. In summary, these results
confirm the traditional medicinal applications of biogenically produced Bismuth
nanoparticles from the aqueous extract of Eclipta
prostrata leaves and highlight its potential as a natural source of free
radical scavengers, antimicrobial, and cytotoxic agents for therapeutic
advancement.
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Pages:98-105
How to cite this article:
P Vijaya Kumari, G Reshma, J Hemapriya, R Elaiyaraja "Biogenic bismuth nanoparticles from <i>Eclipta prostrata</i> Leaves: A natural source of antioxidant, antimicrobial and cytotoxic agents". International Journal of Entomology Research, Vol 10, Issue 9, 2025, Pages 98-105
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