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International Journal of
Entomology Research
ARCHIVES
VOL. 10, ISSUE 7 (2025)
Insects as experimental models in the scientific evaluation of pesticidal efficacy of natural /synthetic compounds and formulation
Authors
Marina Gladys D Souza, Vivek V Byahatti, Mayrui Khairnar, Poonam J Sonawane, Laxmikanth B Borse
Abstract
Insects serve as crucial experimental models in the scientific evaluation of pesticidal compounds. Their varied physiology, short life spans, and genetically tractable systems render them ideal candidates for laboratory-based screening. Widely studied insects such as Drosophila melanogaster, Spodoptera litura, Tribolium castaneum, and Aedes aegypti are frequently employed to assess the potency, specificity, and mechanism of action of pesticides. These species facilitate the identification of effective pest control agents while also aiding in the reduction of adverse effects on non-target species and ecosystems. Model selection is determined by factors such as relevance to agriculture or public health, ease of laboratory cultivation, and response sensitivity. Standard bioassays—including topical, feeding, and fumigation tests—help quantify efficacy through parameters like LC50 or behavioral impact. Moreover, insect-based models contribute to resistance monitoring and ecological safety evaluations, fostering sustainable pest management strategies. With technological advancements, including molecular tools and AI integration, insect bioassays are gaining prominence in developing next-generation pesticidal solutions.
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Pages:121-124
How to cite this article:
Marina Gladys D Souza, Vivek V Byahatti, Mayrui Khairnar, Poonam J Sonawane, Laxmikanth B Borse "Insects as experimental models in the scientific evaluation of pesticidal efficacy of natural /synthetic compounds and formulation". International Journal of Entomology Research, Vol 10, Issue 7, 2025, Pages 121-124
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