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VOL. 10, ISSUE 6 (2025)
Bee venom: From venom to medicine - A comprehensive review of composition, envenoming, and therapeutic Potential
Authors
Prashant L Unde, Narhari G Yedke, Shankar S Yelmame, Laxmikant B Borse
Abstract
Bee venom (BV), a complex secretion of Apis
mellifera and related species, presents a fascinating duality: a
potent threat causing significant morbidity and mortality through envenoming,
and a source of promising therapeutic compounds with diverse biological
activities. This review synthesizes current knowledge on BV composition, the
pathophysiology and management of bee envenoming (particularly mass stinging
events and anaphylaxis), and the rapidly evolving field exploring its
therapeutic applications. We critically examine traditional uses (apitherapy),
modern pharmacological research highlighting anticancer, anti-inflammatory,
antimicrobial, and neuroprotective properties, and the challenges in developing
specific antivenoms. Recent advances in nanotechnology, molecular biology
(e.g., phage display, monoclonal antibodies), and our understanding of venom
biology offer unprecedented opportunities to harness BV's potential while
mitigating its dangers. Standardization of collection, characterization, and
research methodologies is crucial for translating laboratory findings into safe
and effective clinical applications
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Pages:144-150
How to cite this article:
Prashant L Unde, Narhari G Yedke, Shankar S Yelmame, Laxmikant B Borse "Bee venom: From venom to medicine - A comprehensive review of composition, envenoming, and therapeutic Potential". International Journal of Entomology Research, Vol 10, Issue 6, 2025, Pages 144-150
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