Background: Mosquitoes are primary vectors of life-threatening diseases such as malaria, dengue, chikungunya, and filariasis, especially in tropical and subtropical regions. Although chemical repellents are widely used, their associated health hazards and environmental impact necessitate safer alternatives.

Objective: This study aims to formulate and evaluate herbal mosquito repellent sticks using powders of Azadirachta indica (Neem), Ocimum sanctum (Tulasi), Acorus calamus (Sweet Flag), Syzygium aromaticum (Clove), and Cinnamomum verum (Cinnamon) and to assess their physical, combustion, and repellent properties.

Methods: Ten formulations were developed using various combinations of herbal powders and natural excipients. Each formulation was assessed for physical appearance, moisture content, irritability, suffocation, ash value, burning time, smoke visibility, and mosquito repellency in different indoor environments.

Results: All formulations were rod-shaped with smooth surfaces and characteristic herbal odors. Moisture content ranged from 0.5–2%, and no irritability or suffocation effects were observed. Burning time ranged from 15–30 minutes. High smoke visibility and significant mosquito repellent activity were noted, especially in formulations F4, F5, F9, and F10.