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VOL. 10, ISSUE 12 (2025)
Plant-mediated copper oxide nanoparticles as eco-friendly mosquito larvicides: Larval bioassays and computational docking insights
Authors
Dr. K Vijayalakshmi, Dr. N Vidhyulatha
Abstract
The present study principally concentrated on
developing environmentally responsive, plant-mediated, less dangerous copper
oxide nanoparticles (CuO NPs) using Clausena dentata leaf extract and
exploring the mosquito larvicidal action. The biosynthesized CuO NPs were
characterized by UV-Visible, FT-IR, XRD, SEM, and EDX spectroscopy, which
explain the development of CuO NPs. A mosquito larvicidal study of the
green-synthesized CuO NPs was assessed, and the LC50 value of 13.45 µg/mL shows
the strong larvicidal potential of the synthesized NPs. This was further
confirmed by the molecular docking study with mosquito larval protein (PDB
Code: 6XYU), and the binding energy of -5.8 kcal/mol indicates the favorable
contact with the chief amino acid residues. Hence, these findings reveal that
the plant-mediated CuO NPs serve as a promising, ecological agent for mosquito
larvae control.
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Pages:112-116
How to cite this article:
Dr. K Vijayalakshmi, Dr. N Vidhyulatha "Plant-mediated copper oxide nanoparticles as eco-friendly mosquito larvicides: Larval bioassays and computational docking insights". International Journal of Entomology Research, Vol 10, Issue 12, 2025, Pages 112-116
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