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VOL. 10, ISSUE 1 (2025)
Cell damage preventing potential and antimicrobial activities of Pandanus tectorius leaves extract
Authors
T Ramesh, A Amuthavalli
Abstract
Free radicals are unstable molecules missing
an electron and can damage other molecules by taking electrons from them. This
damage can affect intracellular components, potentially causing cell death.
These oxygen-based molecules can harm cells by damaging lipids, proteins, and
DNA. ROS can be produced both within the body and from external sources,
including pollution, cigarette smoke, UV radiation, and heavy metals. When free
radicals are produced faster than the body’s antioxidant defenses can handle,
oxidative stress occurs, leading to damage in cellular structures such as
membranes, proteins, and DNA. Oxidative stress is linked to numerous diseases,
including cancer, asthma, pulmonary hypertension, and retinopathy. Consequences
of oxidative stress may be reduced with aid of antioxidants, which neutralize
free radicals and stop more oxidation processes. Enzymatic and non-enzymatic
elements make up antioxidant system in body. Non-enzymatic molecules from plant
source act in various ways, such as inhibiting enzymes, binding trace elements
that contribute to free radical production, and boosting other antioxidant defenses.
Among these molecules, alkaloids derived from secondary metabolism play a
crucial role in combating oxidative stress. These compounds act as antioxidants
not only because they donate electrons or hydrogen but also because they are
stable in their radical intermediate form. Therefore, studying the ability of
methanolic extracts from Pandanus tectorius to scavenge free radicals
and reduce ROS could help assess the potential of these plants as sources of
novel antioxidant compounds.
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Pages:34-38
How to cite this article:
T Ramesh, A Amuthavalli "Cell damage preventing potential and antimicrobial activities of <i>Pandanus tectorius</i> leaves extract". International Journal of Entomology Research, Vol 10, Issue 1, 2025, Pages 34-38
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