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VOL. 9, ISSUE 9 (2024)
Mosquitocidal, Antioxidant activity and Cytotoxicity of Tarenna alpestris: A medicinal plant from Megamalai Hills, Theni, Tamil Nadu- India
Authors
Chinnappan Sagayaraj, Uthaman Danya
Abstract
Mosquito-borne diseases are illnesses that spread to people by the bite
of an infected mosquito. These illnesses are major public health concerns
worldwide due to their high prevalence, impact on quality of life, and
potential for severe outbreaks. The dengue virus causes the disease, which is
carried by Aedes mosquitos, mainly Aedes aegypti. Dengue fever frequently
causes a high fever, severe headache, pain behind the eyes, joint and muscular
pain, and rash. In severe situations, it can cause dengue hemorrhagic fever and
dengue shock syndrome. Tarenna alpestris, a lesser-known medicinal plant found
in the Megamalai Hills of Theni, Tamil Nadu, India, has attracted attention due
to its possible therapeutic effects. The purpose of this study is to analyze
Tarenna alpestris' pharmacological potential by evaluating its mosquitocidal,
cytotoxic, antioxidant, and efficacious properties. The plant extracts were
produced with hexane solvent and subjected to a variety of tests. To
investigate the plant's potential as an anti-cancer agent, cytotoxicity was
measured using the MTT assay on colon cancer cells HT29. Antioxidant activity
was assessed using DPPH, ABTS, and FRAP tests to determine the ability to
neutralize free radicals. Tarenna alpestris was found to have considerable
cytotoxic effects, namely inhibiting cancer cell proliferation. Its antioxidant
activity was high, with strong radical scavenging properties. These findings
imply that Tarenna alpestris has promising therapeutic potential, which
supports its usage in traditional medicine and calls for additional research
into its bioactive components and mechanisms of action.
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Pages:121-125
How to cite this article:
Chinnappan Sagayaraj, Uthaman Danya "Mosquitocidal, Antioxidant activity and Cytotoxicity of <i>Tarenna alpestris: </i>A medicinal plant from Megamalai Hills, Theni, Tamil Nadu- India". International Journal of Entomology Research, Vol 9, Issue 9, 2024, Pages 121-125
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