The entire world is now facing with a serious issue with food contamination from pesticides. Since the beginning of civilization, agriculture has been severely impacted by the destructive infestation of various pests, including weeds, bacteria, viruses, and fungus, which has resulted in a sharp decline in production. We are polluting and disregarding the state of our natural resources. Farmers are also using numerous types of synthetic chemical pesticides, which are deteriorating the quality of the soil and water, to protect plants from various insect pests and diseases. Because synthetic chemical pesticides persist in the environment for extended periods of time, they are causing a variety of issues related to polluted water, soil, and air. Certain pesticide ingredients are absorbed by plants and build up in their tissues. Through the food chain, these chemicals are passed from one trophic level to another. The animals either die from the greater concentration or have their ability to function impaired. Chlorinated hydrocarbons are thought to be a major contributor to degenerative diseases including cancer and infertility in humans. Thus, we must pay attention to the issues surrounding pesticides and work to find a solution via the biological control of diseases and insect pests. This article will examine the characteristics of beneficial microbial endophytes used in integrated pest control to produce food without pesticides.