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VOL. 9, ISSUE 10 (2024)
Impact of imidacloprid on the mammalian endocrine system: The case of the wistar strain of rattus norvegecus
Authors
Siapo Yao Martin, Kablan Kassi Jean-Jacques, Ano Ehui Joachim, Abeto Claude Joice Dominique, Diby Yao Kan Séraphin, Tahiri Annick
Abstract
Pesticides are chemical substances used to protect plants and their
products. They are intended to curb undesirable organisms. However, they also
have a toxic impact on non-target organisms, particularly humans. To verify the
impact of imidacloprid, a product used in agriculture, we evaluated the
pesticide imidacloprid on the endocrine system of female wistar rats. For the
treatment, doses of 2.25, 4.5 and 9 mg/kg body weight were administered to female
rats for 28 days. With regard to treatment, female rats treated with the 9
mg/kg body weight dose showed a decrease in body weight compared with control
female rats. In terms of vital organ and reproductive mass, there was no
significant variation between treated and control female rats. However,
histopathology showed lesions and dysfunction of the liver, kidneys and
ovaries. Imidacloprid adiminitration caused no disturbance in urea, creatinine,
ALAT, ASAT or estrogen production. Imidacloprid does not cause any apparent
endocrine disruption, but in the long term could have an impact on reproduction
and on the general state of health of human beings.
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Pages:175-180
How to cite this article:
Siapo Yao Martin, Kablan Kassi Jean-Jacques, Ano Ehui Joachim, Abeto Claude Joice Dominique, Diby Yao Kan Séraphin, Tahiri Annick "Impact of imidacloprid on the mammalian endocrine system: The case of the wistar strain of rattus norvegecus". International Journal of Entomology Research, Vol 9, Issue 10, 2024, Pages 175-180
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