Khurja is an important industrial and commercial town in Uttar Pradesh's Bulundshahr region. Pottery and agriculture account for nearly half of Khurja's employment and livelihood. The pottery business directly employs approximately 25,000 people, with an additional 5000-7000 people involved in different support services and linked activities. Trade and commerce, as well as a limited amount of other manufacturing, are other sources of employment in Khurja. Lead leaking into food and drink from ceramics heated with lead glazes is a serious hazard. The Food and Drug Administration (FDA) of the United States and the Canadian Consumer and Corporate Affairs have both set limits on how much lead may leak from food ware into food and drink. Acidic solutions are very dangerous. Keeping these points in view, the present study is undertaken to assess impact of tin oxide and nickel hydroxycrabonate in Channa punctatus (Bloch.).