Insects are the basis for the production of antimicrobial peptides, which act as a line of defense against fungi, bacteria and parasites. Antimicrobial peptides are very effective against the fungal apparatus. The immune system is the first line of defense against pathogens. Peptides show an antimicrobial effect by disrupting the microbial membrane. The complete genome of Tribolium has been published. Antimicrobial peptides can be applied in vaccine development.