The freshwater crab B. cunicularis is a commercially important species and is widely distributed in different regions of Maharashtra, Southern parts of India and Sri Lanka. In freshwater crabs, and many other crustaceans the hepatopancreas is the main digestive gland located in the cephalothorax region of the body. The hepatopancreas is usually considered the most important organ in crustaceans for the storage and mobilization of carbohydrates and lipids, much like the liver of vertebrates and the fat body of insects. The present research work gives a brief account of the histological organization of hepatopancreas and the effect of starvation on the histology of the hepatopancreas. Result obtained shows that the hepatopancreas consists of innumerable, blindly-ending hepatopancreatic tubules held together by means of connective tissues. The hepatopancreatic tubules are surrounded by haemal spaces that contain haemocytes with apparent blood vessels. The hepatopancreatic tubules are enclosed by a basal lamina and each tubule has a central lumen. The study of hepatopancreatic tubule cells shows that these cells can be categorized into three types: R-cells, F- cells and B-cells. Similar observations were also reported earlier by some workers. The R-cells (Reserve cells) are the most common cell type in hepatopancreatic tubules and are characterized by the presence of a large number of cytoplasmic vacuoles. It was observed that starvation results in a lower number of B cells and F-cells in the hepatopancreas.