Bemisia tabaci or whitefly is the major pest of the Okra crop and causes great damage to the crop. This sucks the cell sap and causes the death of the plant. The whitefly has some special characteristics that as the presence of Vasiform orifice which helps in the release of honeydew and protects the insect body from any damage. Begomovirus is spread through the incidence of whitefly on the crop. The coat protein is a special protein that can adapt the transmission of sympatric different species of Bamasia tabaci and this will show the antigenic similarity of coat protein in Begomovirus. The Begomovirus is transmitted through the whitefly (Bemisia tabaci) and they have some antigenically related particles. This will cause natural genomic and antigenic variation in whitefly. This review paper provides complete information about whitefly, its incidence, viral spread in different crops like okra, the transmission of begomovirus through whitefly and natural genomic and antigenic variation in whitefly in okra.