International Journal of Entomology Research

International Journal of Entomology Research


International Journal of Entomology Research
International Journal of Entomology Research
Vol. 7, Issue 2 (2022)

In vitro models for determination of anti-snake venom potential of Erinocarpus nimmonii and Hibiscus punctatus


Harshal Tare

The present study aims to study the anti-snake venom activities of the local plants, which are native to the western ghats of India. These plants were found to be used by traditional healers in Maharashtra, India to treat patients bitten by snakes. The freeze-dried snake venom powder of Daboia russelli was obtained from Hindustan Snake Park, Kolkata. The Erinocarpus nimmonii and Hibiscus punctatus was identified and authenticated by botanist. Extraction of leaves of both plant by hot extraction method and further evaluated for In vitro antivnom activity using three different types of research models, Viz. phospholipase A2 activity, procoagulant activity and Fibrinolytic activity. Plant extracts concentration 0.11 to 0.13 mg for Erinocarpus nimmonii and 0.14 to 0.17mg for Hibiscus punctatus was inhibited PLA2 dependent hemolysis, 1.5 to 1.8 mg for Erinocarpus nimmonii and 1.6 to 1.9 mg for Hibiscus punctatus of plant extracts have shown neutralizing effects in coagulant activity and 0.11 to 0.18 mg for Erinocarpus nimmonii and 0.13 to 0.18 mg for Hibiscus punctatus showed fibrinolytic activity induced by Daboia russelli venom.
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How to cite this article:
Harshal Tare. In vitro models for determination of anti-snake venom potential of Erinocarpus nimmonii and Hibiscus punctatus. International Journal of Entomology Research, Volume 7, Issue 2, 2022, Pages 167-170
International Journal of Entomology Research