Aedes (Stegomyia) aegypti is the primary vector of the dengue virus and infects millions of people throughout the world. The dengue vector has become resistant due to the extensive use of synthetic chemical insecticides and has greatly diminished insecticide efficacy to control mosquito vectors. Thus, the search for new alternative control measures is essential, that can prevent insecticide resistance or decrease the utilization of such chemicals. The aim of the present investigation was to evaluate the larvicidal potential of Prunus persica (Thunb.) leaf extracts against the third instar of Aedes aegypti larvae. The aqueous, ethanolic, and petroleum ether extracts of the leaf were successively tested against the dengue vector. The aqueous extract of the leaf of Prunus persica exhibits the highest larvicidal activity at 500 ppm with LC50 and LC90 values of 179.78 and 524.80 ppm, respectively. Similarly, the petroleum ether extract of the leaf exhibits the highest larvicidal potential at 150 ppm with LC50 and LC90 values of 48.97 and 93.32 ppm, respectively and the ethanolic extract of the leaf showed the highest larvicidal activity at 300 ppm with LC50 and LC90 values of 79.43 and 181.97 ppm, respectively within 24 h post-exposure. All the treatments showed significant (P<0.05) larvicidal activity. Log probit analysis at 95% confidence level reveals the LC50 and LC90, and the results of regression analysis were shown the mortality rate (Y- dependent variable) was positively correlated with the concentration (X- Independent variable). In conclusion, the plant Prunus persica may be a good candidate to be utilized in control programs against the dengue vector, Aedes aegypti.