Objective: Due to chicken meat is an important source of nutrients, the purpose of the study are to show the efficacy of Tomato powder in alleviating the deleterious effects of aflatoxin in broilers and on Growth Performance and Immunological. Methods: One hundred straight-run broiler chicks Ross 308 (one day -old) were used in the present work. In control condition, birds were randomly divided into 5 equal groups, 20 birds for each group as following for 35 days: (G1)20 chicks Basal diet control negative, (G2) 20 chicks Basal diet + aflatoxin (30 ppb) control positiv, (G3) 20 chicks Treated group aflatoxin (30 ppb) + mycofix 3 plus, (G4) 20 chicks Treated group aflatoxin (30 ppb) +Tomato powder %1, (G5) 20 chicks Basal diet +Tomato powder %1. Results: The immunological results showed a significant increase (P˂0.05) in the levels of antibodies against Newcastle Disease and Infectious Bursal Disease for the fourth group (AF&TP) compared with the second group (AF), which showed a significant decrease (P˂0.05) in the same parameters. The results of the body weight in day 7,14,21 and 28 showed a significant increase (P˂0.05) in the fourth group (AF&TP) compared to the second group (AF) for the same results. Conclusion: Tomato powder 1% can be used as a feed supplement in broilers from 1 to 35 days of age to enhance their immune response and body performance. In addition, dietary Tomato powder can replace (Mycofix®).