Arti Sharma, R K Gupta, Kapil Attri, Sumiya Afreen, R S Bandral, Kamlesh Bali
Transgenic technology is the science of intentionally introduction of a foreign gene or genetic construct into the genome of a target animal. The transgenic technology in silkworm provides a new system for the enhancement of anti-viral capacity, production of recombinant human proteins including antibodies and membrane proteins, silkworm strains resistant to BmNPV, production of biomaterials and high toughness silk, development of drugs and high yielding silkworm strains and biomedical applications as drug carriers, sensors or scaffolds for tissue engineering. In addition to this, the transgenic silkworms are also developed to use as a novel animal model for testing medicines based on metabolic similarities between silkworms and mammals. Silkworm has been proven to be one of the most proficient and popularly used eukaryotic expression tools. The silkworm has turn out to be a perfect multicellular eukaryotic model system for basic research.