Arti Sharma, R K Gupta, Palvi Sharma, Jasmeena Qadir, R S Bandral, Kamlesh Bali
Sericulture has undergone a major transformation due to emerging technologies in the field of biotechnology leading to the emergence of newer technologies that have the potential to impact the various aspects of silkworm. Technologies such as gene therapy, gene editing, nano-biotechnology, transgenic technology etc. are being used to address a variety of challenges in silkworm such as producing transgenic silkworms with increased cocoon quality and quantity, to use silk as a biomaterial in medical and pharmaceutical industry etc. The unique characteristics of silk such as strength, elasticity, biodegradability, biocompatibility and mechanical robustness regarding different biomedical uses make it remarkable biomaterial for a wide variety of technical and medical applications. Micrococoons derived from silkworm are an efficient vehicle for drug delivery, a potential approach to treat osteomyelitis and dermal diseases. Silk fibroin and sericin component of silk possesses excellent biocompatibility, controllable biodegradability, remarkable mechanical strength, and low immunogenicity. Therefore, it has been widely used in tissue engineering and regenerative medicine applications such as bone, cartilage, and cornea repair. Bio-nanotechnology advancements lead to the production of silk structures that can be used in water filtration devices, in optics, photonics, in sensors and in drug delivery.
Arti Sharma, R K Gupta, Palvi Sharma, Jasmeena Qadir, R S Bandral, Kamlesh Bali. Technological innovations in sericulture. International Journal of Entomology Research, Volume 7, Issue 1, 2022, Pages 7-15