Influence of non-nutritive sweeteners on stress resistance in Drosophila melanogaster
Amrutha M R, Krishna M S
Environmental changes can decrease fitness which is generally called stress. Nutritional variation also causes stress and influences the fitness, survival and evolutionary approach of organisms. In the present study, flies of Drosophila melanogaster obtained from Non-Nutritive sweeteners aspartame and sucralose, Nutritive sweetener sucrose and control media have been subjected for physiological stresses such as desiccation resistance, chill-coma recovery, heat-shock resistance and starvation resistance. Results reveal that Non-Nutritive Sweeteners have the least resistance to stress when compared to nutritive sweetener sucrose and control flies. Aspartame treated flies had the least resistance to desiccation and recovery from cold treatment and had the highest mortality rate in starvation resistance when compared with Sucralose, nutritive sweetener sucrose and control. However, Aspartame treated flies recovered soon when subjected to heat-shock resistance. Thus, our findings add to the evidence that adult flies treated with non-nutritive sweeteners have a significant impact on the ability to resist stress, and that the type of stress affects the altered nutritional composition in flies.