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VOL. 6, ISSUE 4 (2021)
Efficacy of Cassia fistula against Callosobruchus chinensis (Linn.): An in-silico approach
Authors
Suraj Chetri, Rezina Ahmed, Akalesh Kumar Verma
Abstract
Cassia fistula is a flowering plant belongs to family fabaceae and is widely distributed in tropical countries of the world. Various therapeutic and antibacterial activity of this plant has been studied so far. Callosobruchus chinensis is a major pest of leguminous stored seeds and cause huge amount of damage to seeds every year. The present study emphasizes on the in silico study of interactions of various chemical constituents of C. fistula against enzyme alpha amylase and glutathione S transferase of C. chinensis. The study also aims to find out the mortality rate of C. chinensis when treating them with methanolic crude extract of C. fistula. Among all the selected ligands, physcion shows minimum rerank score of -74.1435 against alpha amylase and phytol shows minimum rerank score of -73.452 against glutathione S transferase. The toxicity test shows that mortality of insects when treated with extract at 2, 4, 6, 8, 10 and 12 % concentration was 28, 35, 43, 53, 67 and 82% respectively and LC50=5.671%. The minimum rerank scores of all selected ligands in in-silico study and the toxicity test results suggest that C. fistula can be potent controlling agent against C. chinensis.
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Pages:202-207
How to cite this article:
Suraj Chetri, Rezina Ahmed, Akalesh Kumar Verma "Efficacy of <em>Cassia fistula</em> against <em>Callosobruchus chinensis</em> (Linn.): An in-silico approach ". International Journal of Entomology Research, Vol 6, Issue 4, 2021, Pages 202-207
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