Azadirachtin and fertacho are two insecticide compounds were exposed to gamma radiation doses of 400 & 700 Gy for potentiating purposes against the pink bollworm, Pectinophora gossypiella (Saund.) treated as 1-4 day old eggs to study the lethal effect of compounds used. In addition to biological and life table parameters of P. gossypiella treated as 1-day old egg by two aforementioned compounds. A dose of 700 Gy can potentiate the efficacy of both tested compounds, followed by a dose of 400 Gy to become the efficacies of azadirachtin and fertacho was higher than the compounds when used singly without exposing to gamma doses. In addition, most of the biological aspects (larval, pupal & adult stages) and life table parameters of female daughter/female (Mx), survival rate (Lx), developmental time, generation time (T), net reproductive rate (Ro), intrinsic rate of natural increase (rm), finite rate of increase (erm) and doubling time for P. gossypiella treated as a 1-day old egg were affected by gamma doses used. So, gamma doses of 700 Gy, followed by 400 Gy can potentiate azadirachtin and fertacho efficacies against P. gossypiella than its efficacies when used singly without exposing to gamma doses.