The different solvent extracts of Pentanema indicum (Asteraceae) are screened for ovicidal and larvicidal activity against S. litura. Qualitative and quantitative test were performed to know richness P. indicum for various bioactive metabolites. The investigation highlighted that methanol extract is more efficient for ovicidal as well as larvicidal activity. Whereas phytochemical analysis revealed the richness of P. indicum for phenolics, flavonoids, tannins and terpenoids and which may be responsible for efficient ovicidal and larvicidal potential of P. indicum. Hence further details study assists us to develop novel botanicals to manage S. litura.