Insecticides are a group of compounds with heterogenous toxicity, whose intended purpose is to kills insects. Synthetic insecticides are known for their very harmful environmental and health impacts. This therefore generates a need for a safer solution. Botanicals are a special group of insecticides with a natural origin, obtained primarily from plant parts. There is a continued interest to screen plants for their insecticidal activities in light of the great destruction done to crops that affect the livelihood of the populace worldwide The aim of the study was to investigate the insecticidal activity of medicinal plants against rice insect pest, Sitophilus oryzae. Two different indigenous plants Artocarpus heterophyllus and Thespesia populnea bark extracts were screenedfor insecticidal activity againstSitophilus oryzae, which is a severepest on rice. Among the plants screened,Thespesia populnea bark extract showed higher activityagainst the selected pest as compared with Artocarpus heterophyllus bark extract. Preliminary phytochemical analysis revealed that the presenceof alkaloid and quinines in the ethanol extract indicate higher percentage of activities.Hence, it may suggest its use for controlling the rice insect pest, Sitophilus oryzae.