Helicoverpa armigera is a major constraint which causes huge losses to tomatoes production up to 85 % of the yields, in Bukina Faso. A study has been done at Kou valley to control this pest and to reduce the damages. The experimentation was a randomized Fisher block design of five treatments (three doses of Cleome viscosa hydroalcoholic formulations, Lambda-chyalotrin + acetamipride 35g EC, with an untreated control) in four replications. The biological efficacy coefficients of the insecticides have been evaluated with the help of Afanasseva et al., formula.The soil microorganisms have been counted on different specific media. C. viscosa hydroalcoholic formulation at the high dose (260.42 L/ha) with a biological efficacy coefficient of 65.21 showed the lowest damage with 10.5% of attacked fruits. It was followed by the normal dose which gave 46.37 efficacity coefficient with 12.00% of attacked fruits. The effects of the high dose were generally comparable to those of Lambda-chyalotrin + acétamipride. The higher dose led to the highest yields (33.26 t/ha) which is a yield increase of 222.47% compared to the untreated control. In addition, the different doses of C. viscosa formulations, stimulated the development of microscopic fungi, celullolytic, ammonifying and nitrifying bacteria in the soil. The bioinsecticide formulation based on C. viscosa leaves, applied at the dose of 260.42 L/ha, effectively controls H. armigera of tomato. It can be recommended as a biopesticide in an integrated pest control programme against H. armigera in tomato production.