Field experiments were carried out in an area of about 16 kirats planted with Cotton varity (Giza 86) during two successive seasons 2018 and 2019 in 12^thMay at Qaha Research Station, Plant Protection Research Institute, Qalyoupia governorate. The selected area was split into 10 plots and control plots. Five products were sprayed Acetamiprid, Thiaclopride, Thiamethoxam (Neonicotinoids), Profenofos (OP), and Flupyradifurone (Butenlides) of recommended dose rates and one treatment left without spraying as control by using Motorized Knapsack sprayer (Agromondo) (20 L./Fed.) and Hydraulic sprayer (Matabi) (56 L/Fed.). Data indicated that, all tested compounds induced significant negative influenced on both Bemisia tabaci and Empoasca discipiens nymphs survival. Profenofos and Flupyradifiurone revealed successful results followed by the other compounds. Results showed that Thiamethoxam and Acetamiprid have lower toxicity and more safe on both Coccinella undecimpunctata and Chrysoprla carnea Larvae, the natural enemies existed. It could be recommended that using those compounds with LV spraying equipment with not less than (20L/Fed.). The data showed that Motorized Knapsack sprayer (Agromondo) (20 L. Fed.) was the best equipment to control both Bemisia tabaci and Empoasca discipiens on Cotton.The rate of performance of Knapsack motor sprayer (Cifarilli) was 12 Fed./day. It was the best equipment, but the lowest rate of performance was Hydraulic sprayer (Matabi) since it could spraying only 3.4 Fed. /day.