Field experiments was conducted in Rabi season during 2017-18 at the farm of Department of Agricultural Entomology, Vasantrao Naik Marathwada Krishi Vidyapeeth, Parbhani (Maharashtra) to study the efficacy of different insecticides against diamondback moth Plutella xylostella and natural enemies in cauliflower. the results revealed that the lowest population of diamondback moth was noticed in emamectin benzoate 5 % SG (2.87/plant), cyantraniliprole 10.26 % OD (2.97/plant), chlorantraniliprole 18.5 % SC (3.06/plant), flubendiamide 20 % WG (3.12/plant), fipronil 5 % SC (4.07/plant) and chlorfenapyr 10 % SC (4.10/plant). Which were at par with each other. The maximum reduction was observed in the plots treated with and emamectin benzoate 5 % SG (53.46 %), cyantraniliprole 10.26 % OD (52.11 %), flubendiamide 20 % WG (48.68 %). The highest curd yield were recorded in treatment emamectin benzoate 5 % SG (17.85 t/ha) which was followed by flubendiamide 20 % WG (17.20 t/ha).