Maize crop provides source of livelihood to all groups of people that depend on it. Its adaptability to different agro-ecological zones has led to its increased production and consumption worldwide. Significant proportion of post-harvest losses of maize grain is attributed to storage insect pests including Sitophilus zeamais (maize weevil) which thrive mostly under tropical climates. Chemical insecticides like carbamates, organophosphates and synthetic pyrethroids used in maize grain protection have raised concerns on undesirable environmental and human health effects as well as effects on non-target organisms owing to their prolonged persistence. A laboratory investigation was carried out to explore the possibility of controlling S. zeamais with admixture of unstabilized pyrethrins and diatomaceous earth in five different ratios of unstabilized pyrethrins and diatomaceous earth but maintaining the application rate at 3g kg-1. Twenty (20) adult S. zeamais were seeded into each glass jar in 4 replicates per treatment. Separately in other glass jars, S. zeamais were treated with pyrethrins alone and diatomaceous earth alone. Untreated maize grains were also seeded with adult S. zeamais (Control). Actellic Super Dust – a commercial grain protectant (containing 1.6% pirimiphos-methyl and 0.3% permethrin) was included for comparison with the admixture. Mortality was monitored in all the treatments at intervals of 7th, 14th, 21st and 28th day. Within the first 7 days the admixture treatments had attained >73% mortality while pyrethrins alone was at 70% mortality and diatomaceous earth alone had induced 13.75% mortality. By end of 28th day, all the treatments had showed 100% mortality except the diatomaceous treatment which was at 90% mortality. Analysis of mortality using one-way ANOVA showed significant differences among the treatments within the first 7 days, but by the 14th day, all the treatments showed no significant differences. Based on the study it is recommended that combinations of unstabilized pyrethrins and diatomaceous earth be utilized as grain storage protectant.