Propolis, byproduct of honey bees, has many anti microbial, antifungal and antitumor properties. Honey develop the Propolis to fasten the holes and fractures and also for restoration of the beehive which helps in lubrication, keeping the internal temperature (35oC) and preventing the attack of predators. It also helps in saving the beehive from environmental erosion and weathering processes. Besides this utilization Propolis also has many benefits in curing various health problems like allergies, gynecological, oral and gastrointestinal disorders. However the accurate procedure in curing the illnesses have not been not completely evaluated and understood that’s why more clearly scientific approach is needed to explore the procedure. This paper deals with review of different therapeutic and biological properties of propolis that are listed and analyzed in past years.