Vol. 4, Issue 1 (2019)
Heat shock proteins as a defense mechanism in midgut and haemocytes of Bombyx mori larvae subjected to various stressors
Author(s): Ann Sandhya Michael, Ananda Kumar MD, Shivashankar M
Abstract: A common physiological response of organisms to environmental stress is the increase in expression of heat shock proteins. In this study, an attempt was made to evaluate the role of HSPs in maintaining the homeostasis of ROS in silkworm, Bombyx mori, and larvae under various stressors. A twenty four hours exposure to cold, hypoxia and nuclear polyhedral virus resulted a significant up regulation of HSP70 and HSP90 in midgut tissue and haemocytes. However, the differential expression of proteins were observed in the tissues. Our results clearly indicate HSPs as a possible transitory defense mechanism afforded by silkworm to lessen the oxidative cellular damage induced by short term stressors. The study also brings an insight into the stressor specific and tissue specific expression of HSPs as an immediate defence mechanism to overcome the oxidative insult.